1243144-97-9

Basic information

• Product Name: methyl 2-(2-bromophenyl)-3-oxobutanoate
• Synonyms: methyl 2-(2-bromophenyl)-3-oxobutanoate
• CAS NO: 1243144-97-9
• Molecular Formula: C₁₁H₁₁BrO₃
• Molecular Weight: 271.10724
• Mol File: 1243144-97-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 320.1±27.0 °C(Predicted)
• Appearance: /
• Density: 1.432±0.06 g/cm3(Predicted)
• PKA: 9.54±0.46(Predicted)
• CAS DataBase Reference: methyl 2-(2-bromophenyl)-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-bromophenyl)-3-oxobutanoate(1243144-97-9)
• EPA Substance Registry System: methyl 2-(2-bromophenyl)-3-oxobutanoate(1243144-97-9)

Safety Data

• Hazardous Substances Data: 1243144-97-9(Hazardous Substances Data)

Upstream product

• 2466-76-4 N-Acetylimidazole 
• 57486-69-8 methyl 2-(2-bromophenyl)acetate 

Downstream Products

• 1621862-74-5 tert-butyl 4-(1-(3-(2-bromophenyl)-4-methoxy-4-oxobut-2-en-2-ylamino)ethyl)piperidine-1-carboxylate 
• 1450724-34-1 (E)-methyl 3-((1-(1,4-dioxan-2-yl)ethyl)imino)-2-(2-bromophenyl)butanoate 
• 1802175-06-9 (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(tetrahydro-2H-pyran-4-yl)ethyl)-1H-indole-3-carboxamide 
• 1802175-06-9 (S)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(tetrahydro-2H-pyran-4-yl)ethyl)-1H-indole-3-carboxamide 
• 1450654-49-5 N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(tetrahydro-2H-pyran-4-yl)ethyl)-1H-indole-3-carboxamide 
• 1802175-07-0 CPI-169 
• 1450658-66-8 (Z)-methyl 2-(2-bromophenyl)-3-((1-(tetrahydro-2H-pyran-4-yl)ethyl)amino)but-2-enoate 
• 1450658-24-8 methyl 1-benzyl-2-methyl-1H-indole-3-carboxylate 

Relevant articles and documents

INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents of formulas (l)/(ll)/(lll) for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

SUBSTITUTED BENZENE AND 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS

The present invention relates to substituted benzene compounds and bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

A practical synthesis of indoles via a Pd-catalyzed C-N ring formation

A method for the synthesis of N-functionalized C2-/C3-substituted indoles via Pd-catalyzed C-N bond coupling of halo-aryl enamines is described. The general strategy utilizes a variety of amines and β-keto esters which are elaborated into halo-aryl enamin