1243202-05-2Relevant academic research and scientific papers
Synthesis, characterization, crystal structure and cytotoxicities of 2-aroyl-3-aryl-5H-furo[3,2-g]chromene derivatives
Wang, Shi-Hui,Wang, Yan,Zhu, Yu-Ying,Han, Jian,Zhou, Yi-Fan,Koirala, Diwa,Li, Da-Wei,Hu, Chun
experimental part, p. 204 - 214 (2010/12/19)
Five 2-aroyl-3-aryl-5H-furo[3,2-g]chromene derivatives have been synthesized, and their structures were characterized by IR, NMR, ESI-MS and elemental analysis. The crystal structure for 2-benzoyl-3-(4-methoxyphenyl)-6,7- dihydro-5H-furo[3,2-g]chromene has been determined by single-crystal X-ray diffraction. X-ray analysis reveals that the pyran ring adopts a half-chair conformation, while the fused furo[3,2-g]chromene ring is approximately coplanar with a slight distortion. The preliminary pharmacological test showed all target compounds exhibit cytotoxicities against the U2OS-EGFP-4F12G cell line. ARKAT USA, Inc.
