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1243263-83-3

1243263-83-3

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1243263-83-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1243263-83-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,3,2,6 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1243263-83:
(9*1)+(8*2)+(7*4)+(6*3)+(5*2)+(4*6)+(3*3)+(2*8)+(1*3)=133
133 % 10 = 3
So 1243263-83-3 is a valid CAS Registry Number.

1243263-83-3Downstream Products

1243263-83-3Relevant articles and documents

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists

Galambos, Janos,Wagner, Gabor,Nogradi, Katalin,Bielik, Attila,Molnar, Laszlo,Bobok, Amrita,Horvath, Attila,Kiss, Bela,Kolok, Sandor,Nagy, Jozsef,Kurko, Dalma,Bakk, Monika L.,Vastag, Monika,Saghy, Katalin,Gyertyan, Istvan,Gal, Krisztina,Greiner, Istvan,Szombathelyi, Zsolt,Keser, Gyoergy M.,Domany, Gyoergy

scheme or table, p. 4371 - 4375 (2010/10/02)

Hit-to-lead optimization of a HTS hit led to new carbamoyloxime derivatives. After identification of an advanced hit (8d) the CYP enzyme inhibitory activity of this class of compounds was successfully eliminated. Systematic exploration of different parts of the advanced hit led us to some promising lead compounds with mGluR5 affinities comparable to that of MPEP.

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