1243264-56-3

Upstream product

• 1351782-57-4 2-(2-bromophenyl)-1-methylimidazole 
• 6630-33-7 ortho-bromobenzaldehyde 
• 741662-26-0 2-(2-bromophenyl)-4,5-dihydro-1H-imidazole 
• 162356-38-9 2-(2-bromophenyl)-1H-imidazole 
• 121-43-7 Trimethyl borate 

Relevant academic research and scientific papers

Catalytic Activation of Cis-Vicinal Diols by Boronic Acids: Site-Selective Acylation of Carbohydrates

Site-selective acylation of unprotected carbohydrates by using stable, storable, and easily handled imidazole-containing organoboronic acid catalysts is described. This catalytic process with low catalyst loading enables the introduction of a wide variety of acyl functional groups into the equatorial position of cis-vicinal diols in unprotected hexapyranosides with excellent site selectivity. This is the first example that uses a Lewis base-containing boronic acid to enhance the nucleophilicity of hydroxy groups.

Intramolecular dehydrative condensation of dicarboxylic acids with brnsted base-assisted boronic acid catalysts

Bifunctional Brnsted base-assisted boronic acid catalysts, arylboronic acids bearing two sterically bulky (N,N-dialkylamino)methyl groups at the 2,6-positions, exhibit remarkable activities for the dehydrative intramolecular condensation of dicarboxylic acids. The steric bulkiness of the (N,N-dialkylamino)methyl groups of 1, which prevents the formation of less active species such as the N→B chelated species and triarylboroxines 3, is crucial for the high catalytic activity. This is the first successful method for the catalytic dehydrative self-condensation of di-and tetracarboxylic acids.