1243325-00-9Relevant articles and documents
Synthesis, characterization and single crystal studies of 3-cyclopropyl-3, 4-dihydroquinazolin-2(1H)-one
Shetty, Nitinkumar S.,Nadaf,Bilehal, Dinesh,Shyamkumar,Gaonkar, Santosh L.
, p. 2707 - 2712 (2016)
The paper describes industrially scalable synthesis and single crystal studies of 3-cyclopropyl-3,4-dihydroquinazolin-2(1H)-one 4, a versatile intermediate in the synthesis of number of biologically active compounds. The target compound has been characterized by LC-MS, 1H NMR and IR. The crystal structure analysis shows that the title compound crystallizes in monoclinic class under the space group P 1 21/n 1 with cell parameters, a = 10.273(2) ?, b = 8.3227(19) ?, c = 11.623(3) ?, β = 104.980(3)°, V = 960.0(4) ?3 and Z=4.
RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
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Page/Page column 23; 24, (2015/05/19)
Compounds of Formula (I): wherein R1, R2 and R3 are defined herein, are useful as inhibitors of RSV.
BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS
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Page/Page column 69, (2010/10/03)
The invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined in the specification, and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together
