124357-52-4Relevant academic research and scientific papers
Novel S-Alkylation Products from "Isolated Thiamin Ylide" via Thiaminium Neothiaminthiolate Ion Pair
Sugimoto, Hirohiko,Ishiba, Teruyuki,Sato, Tomohiro,Nakai, Hiroshi,Hirai, Kentaro
, p. 467 - 470 (1990)
The ambident anion character of thiamin ylide was demonstrated by alkylation reactions of the "isolated thiamin ylide" under neutral or basic conditions.Alkylation with alkyl halides yielded S-alkyl derivatives of the yellow form of thiamin (pyrimidopyrimidine derivatives) instead of 2-alkylthiamin.These and previous results provide chemical evidence that thiamin ylide and thiaminium neothiaminthiolate (8) undergo a facile interconversion in EtOH.
