124378-77-4

Basic information

• Product Name: Enadoline
• Synonyms: Enadoline;N-[(5R,7S,8S)-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decane-8β-yl]-N-methylbenzofuran-4-acetamide;N-[[5R,7S,8S,(-)]-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decane-8β-yl]-N-methylbenzofuran-4-acetamide;N-[[5R,7S,8S,(+)]-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decan-8β-yl]-N-methylbenzofuran-4-acetamide;4-Benzofuranacetamide, N-methyl-N-((5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-;4-Benzofuranacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-, (5R-(5alpha,7alpha,8beta))-;Enadoline [inn];Unii-kjl283326c
• CAS NO: 124378-77-4
• Molecular Formula: C24H32N2O3
• Molecular Weight: 396.528
• Mol File: 124378-77-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 563.2 °C at 760 mmHg
• Flash Point: 294.4 °C
• Appearance: /
• Density: 1.2 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Enadoline(CAS DataBase Reference)
• NIST Chemistry Reference: Enadoline(124378-77-4)
• EPA Substance Registry System: Enadoline(124378-77-4)

Safety Data

• Hazardous Substances Data: 124378-77-4(Hazardous Substances Data)

Usage

Uses

Enadoline is a selective kappa opioid agonist. It exhibits antihyperalgesic and antiallodynic properties.

Brand name

Analgesic.

InChI:InChI=1/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24-/m0/s1

Upstream product

• 113405-12-2 4-benzofuranacetyl chloride 
• 1033267-82-1 (-)-(5α,7α,8β)-N-methyl-N-7-(1-pyrrolidinyl)-1-oxaspiro<4,5>decan-8-amine 

Relevant articles and documents

Aminocyclohexylamides for antiarrhythmic and anesthetic uses.

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