1243853-02-2Relevant academic research and scientific papers
Chromium-Catalyzed Reductive Cleavage of Unactivated Aromatic and Benzylic C-O Bonds
Yuan, Shuqing,Ling, Liang,Tang, Jinghua,Luo, Meiming,Zeng, Xiaoming
supporting information, p. 3343 - 3350 (2021/07/02)
Reductive cleavage of aromatic and benzylic C-O bonds by chromium catalysis is reported. This deoxygenative reaction was promoted by low-cost CrCl 2precatalyst combined with poly(methyl hydrogen siloxane) as the mild reducing agent, providing a strategy in forming reduced motifs by cleavage of unactivated C-O bonds. A range of functional groups such as bromide, chloride, fluoride, hydroxyl, amino, and alkoxycarbonyl can be retained in the reduction.
