124394-38-3Relevant academic research and scientific papers
Use of chloromethyloxirane in heterocyclization reactions with 1,3-dicarbonyl compounds
Sangwan, Naresh K.,Dhindsa, Kuldip Singh
, p. 316 - 318 (2007/10/02)
The reaction of 5,5-dimethylcyclohexane-1,3-dione (7) with chloromethyloxirane (1) in basic medium yields only one heterocyclic derivative, 2,3,4,6,7,8-hexahydro-3-hydroxy-7,7-dimethyl-5H-1-benzopyran-5-one (10) along with normal alkylation products 5,5-dimethyl-3-oxiranylmethoxy-2-cyclohexen-1-one (8) and 3-(3-chloro-2-hydroxypropanyloxy)-5,5-dimethyl-2-cyclohexen-1-one (9).With other 1,3-dicarbonyl compounds namely cyclohexane-1,3-dione (5), dibenzoylmethane (6) and ethyl 2-cyclopentanonecarboxylate (15), no reaction takes place and the starting carbonyl compounds are recovered unchanged while with ethyl acetoacetate (16) no identifiable products are obtained.
