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Deacetylisothiocolchicine is a chemical compound derived from the natural alkaloid isothiocolchicine, which is found in plants of the Colchicum genus. It is a deacetylated form of isothiocolchicine, meaning that the acetate group has been removed from the molecule. This modification can alter the compound's properties and potential applications. Deacetylisothiocolchicine has been studied for its potential therapeutic effects, particularly in the context of neurodegenerative diseases, due to its ability to inhibit certain protein aggregation processes. The compound's structure and activity make it a subject of interest in medicinal chemistry and drug development, as it may offer insights into new treatments for conditions such as Alzheimer's disease and other protein misfolding disorders.

1244-60-6

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1244-60-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1244-60-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,4 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1244-60:
(6*1)+(5*2)+(4*4)+(3*4)+(2*6)+(1*0)=56
56 % 10 = 6
So 1244-60-6 is a valid CAS Registry Number.

1244-60-6Downstream Products

1244-60-6Relevant academic research and scientific papers

Thiocolchicinethiones: Acid Hydrolysis of Natural and iso-Isomers

Muzaffar, Anjum,Brossi, Arnold

, p. 713 - 717 (2007/10/02)

Thioketone 6 was prepared by thiation of isothiocolchicine (3) with Lawesson's reagent.Acid hydrolysis of 9-thiodeoxothiocolchicine (5) and the iso-isomer 6 afforded, in both cases, a similar mixture of deacetylthiocolchicine 2 and deacetylisothiocolchicine 4.Acetylation of 4 afforded isothiocolchicine 3.

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