1244-60-6Relevant academic research and scientific papers
Thiocolchicinethiones: Acid Hydrolysis of Natural and iso-Isomers
Muzaffar, Anjum,Brossi, Arnold
, p. 713 - 717 (2007/10/02)
Thioketone 6 was prepared by thiation of isothiocolchicine (3) with Lawesson's reagent.Acid hydrolysis of 9-thiodeoxothiocolchicine (5) and the iso-isomer 6 afforded, in both cases, a similar mixture of deacetylthiocolchicine 2 and deacetylisothiocolchicine 4.Acetylation of 4 afforded isothiocolchicine 3.
