Basic information

Product Name: Tenofovir Disoproxil Isopropoxycarbonyl
Synonyms: Tenofovir Disoproxil Isopropoxycarbonyl;5-[[(1R)-1-Methyl-2-[6-[(isopropoxycarbonyl)aMino]-9H-purin-9-yl]ethoxy]Methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid Bis(1-Methylethyl) Ester 5-Oxide;(((((1-(6-forMaMido-9H-purin-9-yl)propan-2-yl)oxy)Methyl)phosphoryl)bis(oxy))bis(Methylene) diisopropyl dicarbonate;Tenofovir disoproxil carbaMate;Tenofovir Disoproxil CarbaMate (Related CoMpound H);Tenofovir impurity O;isopropyl (R)-(9-(2-((bis(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)methoxy)propyl)-9H-purin-6-yl)carbamate;Tenofovir Disoproxil Fumarate impurity C
CAS NO:1244022-54-5
Molecular Formula: C23H36N5O12P
Molecular Weight: 605.532001
EINECS: 200-258-5
Product Categories: Anti-virals;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents
Mol File: 1244022-54-5.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: 1.40±0.1 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
Solubility: Aqueous Acid (Soluble), Chloroform (Slightly), DMSO (Slightly), Methanol (Slight
PKA: 9.14±0.10(Predicted)
Stability: Hygroscopic
CAS DataBase Reference: Tenofovir Disoproxil Isopropoxycarbonyl(CAS DataBase Reference)
NIST Chemistry Reference: Tenofovir Disoproxil Isopropoxycarbonyl(1244022-54-5)
EPA Substance Registry System: Tenofovir Disoproxil Isopropoxycarbonyl(1244022-54-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1244022-54-5(Hazardous Substances Data)

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Usage
SDS
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1244022-54-5 Usage

Uses

Used in Pharmaceutical Industry:
Tenofovir Disoproxil Isopropoxycarbonyl is used as an antiviral agent for the treatment of HIV and hepatitis B virus (HBV) infections. It works by inhibiting the viral reverse transcriptase enzyme, thus preventing the replication of the virus within host cells.
Used in Antitumor Applications:
Tenofovir Disoproxil Isopropoxycarbonyl is also used as an antitumor agent, particularly in the treatment of certain types of cancer. Its antiviral properties have been found to have potential applications in cancer therapy, as some viruses are known to be associated with the development of certain malignancies.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of Tenofovir Disoproxil Isopropoxycarbonyl, various drug delivery systems have been developed. These systems aim to improve the compound's delivery to target cells, reduce side effects, and increase its overall therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 1244022-54-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,4,0,2 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1244022-54:
(9*1)+(8*2)+(7*4)+(6*4)+(5*0)+(4*2)+(3*2)+(2*5)+(1*4)=105
105 % 10 = 5
So 1244022-54-5 is a valid CAS Registry Number.

1244022-54-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name	propan-2-yl [[(2R)-1-[6-(propan-2-yloxycarbonylamino)purin-9-yl]propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl carbonate

1.2 Other means of identification

Product number	-
Other names	Tenofovir Disoproxil Isopropoxycarbonyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1244022-54-5 SDS

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