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Usage

Uses

Used in Pharmaceutical Research:
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-piperidinyl)cyclohexyl]-Thiourea is used as a candidate for pharmaceutical development due to its potential therapeutic effects. N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-piperidinyl)cyclohexyl]-Thiourea's unique structural features, including the trifluoromethylphenyl and piperidine-cyclohexyl groups, may offer specific biological activities that could be harnessed for medicinal purposes.
Used in Disease Treatment:
While the precise applications are still under investigation, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-piperidinyl)cyclohexyl]-Thiourea is being studied for its potential role in treating a variety of diseases and conditions. Its use in this context is based on the compound's demonstrated promise in preclinical research, although further studies are necessary to confirm its efficacy and safety in clinical settings.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-piperidinyl)cyclohexyl]-Thiourea serves as a subject of research to understand its interaction with biological targets and its potential as a lead compound for drug development. N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-piperidinyl)cyclohexyl]-Thiourea's structure may be optimized to enhance its pharmacological properties and selectivity for specific therapeutic applications.
Used in Drug Discovery:
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-piperidinyl)cyclohexyl]-Thiourea is utilized in drug discovery processes to identify new molecular entities with therapeutic potential. Its unique chemical structure provides a starting point for the design and synthesis of novel compounds that may exhibit improved pharmacological profiles compared to existing treatments.

Upstream product

• 824938-80-9 (1S, 2S)-trans-2-(1-piperidinyl)cyclohexylamine 
• 23165-29-9 3,5-bistrifluoromethylphenylisothiocyanate 
• 21436-03-3 (S,S)-1,2-diaminocyclohexane 
• 111-30-8 Glutaraldehyde 

Relevant academic research and scientific papers

Organocatalytic asymmetric conjugate addition of malonates to 3-nitro-2H-chromenes

The conjugate addition of malonates to 3-nitro-2H-chromenes has been studied in the presence of a number of chiral organocatalysts. A bifunctional thiourea-tertiary amine was found to be an efficient catalyst for the reaction. Good yields and enantioselec

Organocatalytic Enantio- and Diastereoselective Construction of syn-1,3-Diol Motifs via Dynamic Kinetic Resolution of in Situ Generated Chiral Cyanohydrins

An organocatalytic method for the asymmetric synthesis of syn-1,3-dioxanes as protected 1,3-diols via dynamic kinetic resolution of in situ generated chiral cyanohydrins has been developed. This method involves a reversible cyanohydrin formation/hemiaceta

Asymmetric cycloetherification of in situ generated cyanohydrins through the concomitant construction of three chiral carbon centers

The organocatalytic enantio- A nd diastereoselective cycloetherification of in situ generated cyanohydrins through the concomitant construction of three chiral carbon centers is reported. This protocol facilitates the concise synthesis of optically active

Kinetic Resolution of Acylsilane Cyanohydrins via Organocatalytic Cycloetherification

An asymmetric cyanation of acylsilanes involving the in-situ formation of chiral acylsilane cyanohydrins followed by their kinetic resolution via organocatalytic cycloetherification is described. The highly enantio- and diastereoselective cycloetherificat

Metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea

The first metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea to form multiply substituted pyrrolidines in excellent yields (up to 89%) and enantioselectivities (up to 96% ee) is presented. This procedure allows a rapid diversity-oriented synthesis of chiral pyrrolidine derivatives with high optical purity. A series of bifunctional thiourea catalysts were applied for the first time to the highly asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides togive the products in excellent yields (up to 89%) and enantioselectivities (up to 96% ee).