124409-62-7

Upstream product

• 93489-58-8 (3aR,4S,7aS)-(Z)-1-ethylidene-7a-methyloctahydro-1H-4-indenol 
• 93489-59-9 [1R-(3aβ(S*),7β,7aα)]-β,3a-dimethyl-4-hydroxy-(3a,4,5,6,7,7a)hexahydro-1H-indene-1-ethanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 124409-74-1 Toluene-4-sulfonic acid (S)-2-((3aR,4S,7aS)-7a-methyl-4-triethylsilanyloxy-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-propyl ester 
• 212124-41-9 (R)-2,2-Difluoro-5-((3aR,4S,7aS)-7a-methyl-4-triethylsilanyloxy-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-3-phenoxythiocarbonyloxy-hexanoic acid ethyl ester 

Relevant academic research and scientific papers

Noncalcemic, antiproliferative, transcriptionally active, 24-fluorinated hybrid analogues of the hormone 1α,25-dihydroxyvitamin D3. Synthesis and preliminary biological evaluation

Four new hybrid analogues of 1α,25-dihydroxyvitamim D3 (1) have been synthesized in a convergent manner by joining A-ring and C,D-ring fragments. Each hybrid analogue, having a noncalcemic 1-hydroxymethyl group and a potentiating 16-ene 24,24-d