124409-86-5Relevant articles and documents
An efficient synthesis of ofloxacin and levofloxacin from 3,4- difluoroaniline
Adrio, Javier,Carretero, Juan C.,Garcia Ruano, Jose L.,Pallares, Antonio,Vicioso, Mercedes
, p. 1563 - 1572 (2007/10/03)
The functionalization at either C-2 or C-3 of N-(tert-butoxycarbonyl)- 3,4-difluoroaniline based on its ortho-deprotonation under different experimental conditions is described. This kind of products can be readily applied to the synthesis of ofloxacin, levofloxacin and related compounds.