124409-86-5

Basic information

• Product Name: diethyl [3,4-difluoro-2-(2-hydroxypropyloxy)anilinyl]methylenemalonate
• Synonyms: diethyl [3,4-difluoro-2-(2-hydroxypropyloxy)anilinyl]methylenemalonate
• CAS NO: 124409-86-5
• Molecular Weight: 373.354
• Mol File: 124409-86-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl [3,4-difluoro-2-(2-hydroxypropyloxy)anilinyl]methylenemalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl [3,4-difluoro-2-(2-hydroxypropyloxy)anilinyl]methylenemalonate(124409-86-5)
• EPA Substance Registry System: diethyl [3,4-difluoro-2-(2-hydroxypropyloxy)anilinyl]methylenemalonate(124409-86-5)

Safety Data

• Hazardous Substances Data: 124409-86-5(Hazardous Substances Data)

Upstream product

• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 144298-04-4 (3,4-difluorophenyl)-carbamic acid-tert-butyl ester 
• 115551-33-2 2-hydroxy 3,4-difluoro aniline 
• 85741-74-8 diethyl 2-(((3,4-difluoro-2-hydroxyphenyl)amino)methylene)malonate 
• 75-56-9 methyloxirane 

Downstream Products

• 82419-35-0 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid 
• 82419-36-1 ofloxacin 

Relevant articles and documents

An efficient synthesis of ofloxacin and levofloxacin from 3,4- difluoroaniline

The functionalization at either C-2 or C-3 of N-(tert-butoxycarbonyl)- 3,4-difluoroaniline based on its ortho-deprotonation under different experimental conditions is described. This kind of products can be readily applied to the synthesis of ofloxacin, levofloxacin and related compounds.