124428-38-2 Usage
Family
Quinazoline derivatives
Function
Inhibitor of anaplastic lymphoma kinase (ALK)
Potential use
Treatment of ALK-positive cancers
Structure
Quinazoline core with a fluorine atom at position 8 and an ethoxy group attached to a 3,4-dimethoxyphenyl group
Mechanism of action
Interacts with the ATP-binding pocket of the ALK enzyme, inhibiting its activity and potentially slowing cancer progression.
Check Digit Verification of cas no
The CAS Registry Mumber 124428-38-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,4,2 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 124428-38:
(8*1)+(7*2)+(6*4)+(5*4)+(4*2)+(3*8)+(2*3)+(1*8)=112
112 % 10 = 2
So 124428-38-2 is a valid CAS Registry Number.