124446-44-2

Upstream product

• 124446-98-6 N-(2-hydroxy-2-phenylethyl) N-methyl thiophene-3-ethylamine 

Downstream Products

• 124446-53-3 6-methyl-8-phenyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine-2-carboxaldehyde 
• 124446-69-1 3-Bromo-6-methyl-8-phenyl-5,6,7,8-tetrahydro-4H-thieno [2,3-d]azepine 

Relevant academic research and scientific papers

Thieno[2,3-O]azepine compounds and CNS affecting use thereof

Compounds of the formula STR1 in which R1 is hydrogen, hydroxy, nitro, cyano, halo, amino, acetamido, hydroxy-C1-4 alkyl, carboxaldehydo, C1-4 alkylcarbonyl, carboxy, C1-4 alkoxy-carbonyl, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl or C1-4 alkoxy-C1-4 alkyl, R2 is hydrogen, hydroxy, nitro, cyano, halo, amino, carboxamido, acetamido, hydroxy-C1-4 alkyl, carboxyaldehydo, C1-4 alkylcarbonyl, carboxy, C1-4 alkoxycarbonyl, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, C1-4 alkoxy-C1-4 alkyl, oximino or aminomethyl, R3 is optionally substituted phenyl or optionally substituted phenyl ortho condensed with an optionally substituted ring selected from benzene, cyclohexane, cyclohexene, cyclopentane or cyclopentene, in which ring one of the carbon atoms may be replaced by oxygen, sulphur or nitrogen, and R4 is hydrogen, C1-4 alkyl, C2-4 alkenyl or optionally substituted benzyl; and salts thereof; have central nervous system activity.