1244469-13-3

Basic information

• Product Name: 6-isopropyl-4-(2-isopropylphenyl)-2H-cromen-2-one
• CAS NO: 1244469-13-3
• Molecular Weight: 306.404
• Mol File: 1244469-13-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-isopropyl-4-(2-isopropylphenyl)-2H-cromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-isopropyl-4-(2-isopropylphenyl)-2H-cromen-2-one(1244469-13-3)
• EPA Substance Registry System: 6-isopropyl-4-(2-isopropylphenyl)-2H-cromen-2-one(1244469-13-3)

Safety Data

• Hazardous Substances Data: 1244469-13-3(Hazardous Substances Data)

Upstream product

• 1244469-19-9 4-bromo-6-isopropyl-2H-cromen-2-one 
• 89787-12-2 2-isopropylphenylboronic acid 

Relevant articles and documents

Stereomutation of axially chiral aryl coumarins

Coumarins substituted by an aryl group in position 4 display restricted rotation about the Ar-C4 bond, giving rise to conformational or configurational enantiomers (atropisomers) when such a restricted motion leads to a C 1 symmetry. The dynamics of the stereomutation processes of these axial enantiomers was monitored by dynamic NMR, dynamic enantioselective HPLC, or racemization kinetics, depending on the activation energies involved. These results were further supported by DFT computations. In the two cases where the enantiomers were sufficiently long living as to be physically separated at ambient temperature, the absolute configuration was determined by means of a theoretical simulation of their electronic circular dicroism spectra (ECD).