1244737-85-6

Basic information

• Product Name: N-cyclohexyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
• Synonyms: N-cyclohexyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
• CAS NO: 1244737-85-6
• Molecular Weight: 258.363
• Mol File: 1244737-85-6.mol

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamide(1244737-85-6)
• EPA Substance Registry System: N-cyclohexyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamide(1244737-85-6)

Safety Data

• Hazardous Substances Data: 1244737-85-6(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1244737-60-7 2-benzyloxycarbonyl-1-cyclohexylcarbamoyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

An Ugi Reaction Incorporating a Redox-Neutral Amine C-H Functionalization Step

Pyrrolidine and 1,2,3,4-tetrahydroisoquinoline (THIQ) undergo redox-neutral α-amidation with concurrent N-alkylation upon reaction with aromatic aldehydes and isocyanides. Reactions are promoted by acetic acid and represent a new variant of the Ugi reacti

Convenient synthesis of 1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid derivatives via isocyanide-based, three-component reactions

The three-component reactions of 3,4-dihydroisoquinolines, isocyanides, and benzyl chloroformate furnished 2-benzyloxycarbonyl-1,2,3,4- tetrahydroisoquinoline-1-carboxamides in moderate to good yields. Hydrogenolysis or selective hydrolysis of the benzylo