1244760-92-6

Basic information

• Product Name: C₂₃H₂₇N₇O
• CAS NO: 1244760-92-6
• Molecular Weight: 417.514
• Mol File: 1244760-92-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₇N₇O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₇N₇O(1244760-92-6)
• EPA Substance Registry System: C₂₃H₂₇N₇O(1244760-92-6)

Safety Data

• Hazardous Substances Data: 1244760-92-6(Hazardous Substances Data)

Upstream product

• 5521-55-1 2-methylpyrazin-5-carboxylic acid 
• 1244760-73-3 C₁₇H₂₃N₅ 

Relevant articles and documents

Pyridine carboxamides: Potent palm site inhibitors of HCV NS5B polymerase

Pyridine carboxamide-based inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified and optimized to a variety of topologically related scaffolds. In particular, the 2-methyl nicotinic acid scaffold was developed into inhibitors with improved biochemical (IC50-GT1b = 0.014 μM) and cell-based HCV replicon potency (EC50-GT1b = 0.7 μM). Biophysical and biochemical characterization identified this novel series of compounds as palm site binders to HCV polymerase.