1244783-57-0

Basic information

• Product Name: C₂₈H₃₇N₃O₇
• CAS NO: 1244783-57-0
• Molecular Weight: 527.618
• Mol File: 1244783-57-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₇N₃O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₇N₃O₇(1244783-57-0)
• EPA Substance Registry System: C₂₈H₃₇N₃O₇(1244783-57-0)

Safety Data

• Hazardous Substances Data: 1244783-57-0(Hazardous Substances Data)

Upstream product

• 7456-87-3 carbonic acid monomethyl ester 
• 2769-64-4 n-butyl isonitrile 
• 1076-95-5 p-methoxyphenylglyoxal 
• 849020-94-6 tert-butyl (2-(aminomethyl)phenyl)carbamate 

Downstream Products

• 1244783-66-1 C₂₃H₂₇N₃O₄ 

Relevant articles and documents

Concise preparation of novel tricyclic chemotypes: Fused hydantoin-benzodiazepines

The following article describes a concise synthesis of a collection of 4,5-dihydro-1H-benzo[e][1,4]diazepines fused to a hydantoin ring. Molecular complexity and biological relevance are high and structures are generated in a mere three steps, employing the Ugi reaction to assemble diversity reagents. The protocol represents a novel UDC (Ugi-deprotect-cyclize) strategy employed in the Ugi-5-component CO2-mediated condensation, followed by further cyclization under basic conditions, to afford the fused hydantoin. Mechanistic caveats, dependent on the aldehydes of choice will be revealed and a facile oxidation of the final products to imidazolidenetriones is briefly discussed.