1244784-75-5

Upstream product

• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 1244784-67-5 benzyl 14-(tert-butyldimethylsiloxy)-2-hydroxytetradecanoate 
• 1244784-71-1 benzyl (S)-14-(tert-butyldimethylsiloxy)-2-hydroxytetradecanoate 
• 1244784-74-4 C₃₅H₅₆O₅Si 

Downstream Products

• 914936-41-7 (2S)-14-(t-butyldimethylsiloxy)-1-(t-butyldiphenylsiloxy)-2-(p-methoxybenzyloxy)tetradecane 
• 914936-85-9 (13S)-14-(t-butyldiphenylsiloxy)-13-(p-methoxybenzyloxy)tetradecanol 
• 914936-43-9 (2S)-1-(t-butyldiphenylsiloxy)-14-iodo-2-(p-methoxybenzyloxy)tetradecane 

Relevant academic research and scientific papers

METHOD FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXY ESTER AND NOVEL INTERMEDIATE COMPOUND

Disclosed is a method for producing an optically active 2-hydroxy ester, comprising selectively esterifying one enantiomer of a racemic 2-hydroxy ester in a solvent containing a catalyst such as tetramisole or benzotetramisole, and a carboxylic acid anhydride, or a carboxylic acid anhydride and a carboxylic acid. In particular, in the case where the solvent contains a carboxylic acid anhydride, but does not contain a carboxylic acid, as the carboxylic acid anhydride, a carboxylic acid anhydride containing a tertiary or quaternary carbon atom in the a-position is used. On the other hand, in the case where the solvent contains a carboxylic acid anhydride and a carboxylic acid, as the carboxylic acid, a carboxylic acid containing a tertiary or quaternary carbon atom in the a-position is used.