1244863-67-9Relevant academic research and scientific papers
2-Aryl benzimidazoles featuring alkyl-linked pendant alcohols and amines as inhibitors of checkpoint kinase Chk2
Neff, Danielle K.,Lee-Dutra, Alice,Blevitt, Jonathan M.,Axe, Frank U.,Hack, Michael D.,Buma, Johnathan C.,Rynberg, Raymond,Brunmark, Anders,Karlsson, Lars,Breitenbucher, J. Guy
, p. 6467 - 6471 (2008/09/17)
A series of benzimidazole compounds containing pendant alcohol and amine moieties was found to be active against checkpoint kinase Chk2. These compounds were prepared to examine a potential hydrogen bond interaction with an active site residue and to inve
