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1244954-14-0

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1244954-14-0 Usage

General Description

The chemical compound (1R,4S)-1,2,3,4-Tetrahydro-1,4-epoxynaphthalene-1-carboxylic Acid, also known as THNCA, is a synthetic intermediate in the production of the anticancer drug camptothecin. It is an epoxide derivative of naphthalene and is used in the synthesis of camptothecin analogs, which have shown potential in cancer treatment. THNCA undergoes various chemical conversions and modifications to ultimately produce camptothecin analogs with improved pharmaceutical properties. Its structure and reactivity make it a key component in the development of new cancer-fighting drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 1244954-14-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,4,9,5 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1244954-14:
(9*1)+(8*2)+(7*4)+(6*4)+(5*9)+(4*5)+(3*4)+(2*1)+(1*4)=160
160 % 10 = 0
So 1244954-14-0 is a valid CAS Registry Number.

1244954-14-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R,4S)-1,2,3,4-Tetrahydro-1,4-epoxynaphthalene-1-carboxylic Acid

1.2 Other means of identification

Product number -
Other names ()-THENA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1244954-14-0 SDS

1244954-14-0Downstream Products

1244954-14-0Relevant articles and documents

Tetrahydro-1,4-epoxynaphthalene-1-carboxylic acid: A chiral derivatizing agent for the determination of the absolute configuration of secondary alcohols

Sungsuwan, Suttipun,Ruangsupapichart, Nopporn,Prabpai, Samran,Kongsaeree, Palangpon,Thongpanchang, Tienthong

supporting information; experimental part, p. 4965 - 4967 (2011/01/12)

A new chiral derivatizing agent, tetrahydro-1,4-epoxynaphthalene-1- carboxylic acid (THENA), with a represented syn-periplanar disposition of O-Ca-CαO as a part of the bicyclic system to lock the aromatic residue conformation and the availability of an in

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