124500-61-4Relevant articles and documents
INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY
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Page/Page column 101, (2019/08/26)
The present disclosure relates to compounds that are capable of modulating the WNT/Beta-Catenin pathway. The disclosure further relates to methods of treating colorectal cancer and other WNT/Beta-Catenin mediated cancers.
INHIBITORS OF C-FMS KINASE
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Page/Page column 36, (2008/06/13)
The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, es
Halobenzene liquid crystals
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, (2008/06/13)
Compounds of the formula STR1 wherein X1 denotes fluorine or chlorine and X2 denotes hydrogen, fluorine or chlorine; R1 is 3E-alkenyl, 4-alkenyl, 2E-alkenyloxy or 3-alkenyloxy; n stands for the number 0 or 1; one of the groups Y1 and Y2 is a single covalent bond, --COO--, --OOC--, --CH2 CH2 --, --CH2 O-- or --OCH2 -- and the other of the groups Y1 and Y2 is a single covalent bond; and rings A1 and A2 each individually are substituted or unsubstituted trans-1,4-cyclohexylene, in which optionally 2 non-adjacent CH2 groups are replaced by oxygen, or substituted or unsubstituted 1,4-phenylene, in which optionally 1 CH group or 2 CH groups is/are replaced by nitrogen; with the proviso that X2 denotes fluorine or chlorine and/or Y1 or Y2 denotes --CH2 O-- or --OCH2 -- when simultaneously X1 is fluorine and R1 is 3E-alkenyl, and their use for liquid crystalline mixtures and electro-optical purposes.