1245124-46-2Relevant academic research and scientific papers
Efficient cycloisomerization of propargyl amides by electrophilic gold(I) complexes of KITPHOS monophosphines: A comparative study
Doherty, Simon,Knight, Julian G.,Hashmi, A. Stephen K.,Smyth, Catherine H.,Ward, Nicholas A. B.,Robson, Katharine J.,Tweedley, Sophie,Harrington, Ross W.,Clegg, William
, p. 4139 - 4147 (2010/12/19)
Electrophilic gold(I) complexes of diphenyl- and dicyclohexylphosphino- based KITPHOS monophosphines catalyze the 5-exo-dig cycloisomerization of a range of propargyl amides to afford the corresponding alkylidene oxazolines; in all cases catalysts formed from diphenylphosphino-substituted KITPHOS monophosphines outperformed their dicyclohexylphosphino counterparts as well as that based on triphenylphosphine, an indication that the biaryl/biaryl-like framework may be responsible for imparting high catalyst efficiency.
