124516-96-7

Upstream product

• 124516-90-1 methyl (4R,5R)-4-(dimethyl-t-butylsilyloxy)-4,5-dihydro-5-methoxyfuran-2-carboxylate 
• 124516-93-4 dimethyl 2-<(4R,5R)-4-(dimethyl-t-butylsilyloxy)-4,5-dihydro-5-methoxyfuran-2-ylmethyl>propanedioate 
• 124516-94-5 methyl <(4R,5R)-4-(dimethyl-t-butylsilyloxy)-4,5-dihydro-5-methoxyfuran-2-yl>propanoate 
• 124516-92-3 (4R,5R)-4-(dimethyl-t-butylsilyloxy)-4,5-dihydro-5-methoxyfuran-2-ylmethyl acetate 
• 85950-35-2 1,2-O-isopropylidene-3-O-toluene-p-sulphonyl-α-D-xylofuranuronic acid 
• 124516-95-6 (4R,5R)-2-(3-benzyloxypropyl)-4-(dimethyl-t-butylsilyloxy)-4,5-dihydro-5-methoxyfuran 

Downstream Products

• 124516-98-9 2-(2-benzyloxyethyl)-4-methoxycyclopent-2-enone 
• 124516-97-8 (4R)-2-(2-benzyloxyethyl)-4-(dimethyl-t-butylsilyloxy)cyclopent-2-enone 

Relevant academic research and scientific papers

A New Route to Optically Active (4R)-2-Substituted 4-Hydroxycyclopent-2-enones from D-Glucose

A synthetic sequence, starting from diacetoneglucose, is developed for optically active (4R)-2-(dimethyl-t-butylsilyloxy)-4-oxo aldehyde (2).The key step is the regioselective palladium-catalysed allylation of malonate with the allylic acetate (4).The 4-oxo aldehyde (2) undergoes Ba(OH)2 cyclization to the optically active (4R)-4-(dimethyl-t-butylsilyloxy)cyclopent-2-enone derivative (1).