1245285-89-5

Upstream product

• 4276-09-9 (R)-2-amino-3-methylbutanol 
• 100-44-7 benzyl chloride 
• 72631-67-5 (1R,4S,5R,8R)-8-benzyloxy-2,6-dioxabicyclo<3.3.0>octan-4-ol 
• 652-67-5 Isosorbide 

Relevant academic research and scientific papers

Synthesis of a new class of ligands derived from isosorbide and their application to asymmetric reduction of aromatic ketones by transfer hydrogenation

A new class of β-amino alcohol and diamine ligands has been prepared from isosorbide as a chiral renewable source. The efficiency of these ligands has been evaluated for the metal-catalyzed enantioselective reduction of aromatic ketones by transfer hydrogenation, giving excellent conversion and good enantioselectivity.

New class of chiral ligands derived from isosorbide: First application in asymmetric transfer hydrogenation

A new class of β-amino alcohol and diamine ligands was prepared from isosorbide as a chiral renewable resource. The original wedge-shaped structure of isosorbide offers an interesting chiral pocket to promote the metal-catalyzed enantioselective reduction of ketones by transfer hydrogenation.