1245559-90-3Relevant academic research and scientific papers
HIGHLY SELECTIVE 5-HT(2C) RECEPTOR AGONISTS HAVING ANTAGONIST ACTIVITY AT THE 5-HT(2B) RECEPTOR
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Page/Page column 22, (2011/09/14)
Highly selective 5-HT(2C) receptor agonists receptors are disclosed. The 5-HT(2C) receptor agonists are used in he treatments of disease and conditions wherein modulation of 5-HT(2C) receptors provides a benefit, such as obesity and psychiatric disorders.
HTS and rational drug design to generate a class of 5-HT 2C-selective ligands for possible use in schizophrenia
Kozikowski, Alan P.,Cho, Sung Jin,Jensen, Niels H.,Allen, John A.,Svennebring, Andreas M.,Roth, Bryan L.
experimental part, p. 1221 - 1225 (2011/02/21)
(Chemical Equation Presented) Treating neurological conditions: Optimization of a previously identified lead 5-HT2C agonist (left) led to the discovery of a highly selective 5-HT2C agonist (right). Importantly, this compound is a 5-H
