1245640-79-2Relevant academic research and scientific papers
Synthesis of new 3-(4-fluoronaphthyl)-5-(aryl)-2-isoxazolines and their antimicrobial and spermicidal activity
Sharma, Sharda,Pathak, Late V. N.,Madan, Harsha,Sharma, Arvind
, p. 337 - 340 (2011/12/22)
Microwave assisted synthesis of 3-(4-fluoronaphthyl)-5-(aryl)-2- isoxazolines (3) from corresponding chalcones (2) and hydroxylamine hydrochloride has been accomplished. Structures of synthesized compounds have been confirmed on the basis of spectral studies (IR, 1H NMR) and analytical data. Representative compounds have been screened for their spermicidal activity in HF cattle and were also evaluated for their antibacterial activity against Staphylococcus aureus, E coli, Pseudomonas and antifungal activity against Candida albicans, Asperigillus niger, Fusarium oxysporum.
