1245641-40-0

Upstream product

• 1245641-38-6 2,3,4,5-tetra-O-acetyl-1-deoxy-1-(N-acetyl-N-2-pyridinylamino)-D-mannitol 
• 1245641-31-9 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-2,3-di-O-benzoyl-α-L-fucopyranosyl trichloroacetimidate 

Relevant academic research and scientific papers

Synthesis of fluorescence-labeled galβ1-3Fuc and Galβ1-4Fuc as Probes for the endogenous glyco-epitope recognized by galectins in caenorhabditis elegans

To search for the endogenous glyco-epitope in Caenorhabditis elegans, we synthesized labeled Galβ1-3Fuc and Galβ1-4Fuc and examined their binding affinity for C. elegans galectin LEC-6 using frontal affinity chromatography analysis. We developed a new strategy for synthesizing the labeled saccharides, in which the labeling unit, the 2-aminopyridine moiety, is coupled with a spacer unit derived from D-mannitol. Our results indicate that Galβ1-4Fuc is the endogenous glyco-epitope present in C. elegans N-glycans.