1245643-77-9 Usage
Description
Ethyl 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylate is a chemical compound belonging to the triazole family, characterized by a molecular formula of C12H10F3N3O2. Its unique structure, featuring a trifluoromethyl group, contributes to its potential for enhanced bioactivity and metabolic stability in medicinal chemistry applications.
Uses
Used in Pharmaceutical Industry:
Ethyl 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylate is used as a key intermediate in the synthesis of pharmaceuticals for the treatment of various diseases. The presence of the trifluoromethyl group in its structure enhances the bioactivity and metabolic stability of the resulting drug molecules, making it a valuable component in drug development.
Used in Agrochemical Industry:
In the agrochemical sector, ethyl 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylate serves as a building block for the creation of novel agrochemicals. Its unique properties can contribute to the development of more effective and stable pesticides or other agricultural chemicals.
Used in Materials Science:
Ethyl 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylate is utilized in the synthesis of new materials with unique properties. Its incorporation into materials can lead to the development of advanced materials with improved characteristics for various applications in science and industry.
It is crucial to handle ethyl 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylate with care and adhere to proper safety protocols when working with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1245643-77-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,6,4 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1245643-77:
(9*1)+(8*2)+(7*4)+(6*5)+(5*6)+(4*4)+(3*3)+(2*7)+(1*7)=159
159 % 10 = 9
So 1245643-77-9 is a valid CAS Registry Number.
1245643-77-9Relevant articles and documents
Flow synthesis of ethyl isocyanoacetate enabling the telescoped synthesis of 1,2,4-triazoles and pyrrolo-[1,2-c]pyrimidines
Baumann, Marcus,Rodriguez Garcia, Antonio M.,Baxendale, Ian R.
, p. 4231 - 4239 (2015)
The efficient flow synthesis of important heterocyclic building blocks based on the 1,2,4-triazole and pyrrolo[1,2-c]pyrimidine scaffold has been achieved. Crucially, a telescoped continuous flow process was developed based on the reaction of N-formylglycine with triphosgene to deliver a stream of ethyl isocyanoacetate in situ, which subsequently yielded the desired heterocyclic entities in a telescoped reaction. Additionally, the functionalisation of the pyrrolo[1,2-c]pyrimidine core via subsequent SEAr reactions was studied revealing insight into a 'halogen dance' phenomenon associated with these medicinally relevant architectures. This journal is
