1245645-54-8

Basic information

• Product Name: ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate
• Synonyms: ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate
• CAS NO: 1245645-54-8
• Molecular Formula: C₁₂H₁₃N₃O₂
• Molecular Weight: 231.25052
• Mol File: 1245645-54-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate(1245645-54-8)
• EPA Substance Registry System: ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate(1245645-54-8)

Safety Data

• Hazardous Substances Data: 1245645-54-8(Hazardous Substances Data)

Usage

General Description

Ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate is a chemical compound with the molecular formula C12H13N3O2. It belongs to the class of organic compounds known as triazoles and is commonly used in the synthesis of pharmaceuticals and agrochemicals. This chemical is characterized by its triazole ring structure, which has potential biological activity. Ethyl 1-p-tolyl-1H-1,2,4-triazole-3-carboxylate may have applications in the development of new drugs and insecticides. Its unique structure and potential biological properties make it a subject of interest for further research and development in the field of medicinal and agricultural chemistry.

Upstream product

• 2999-46-4 Ethyl isocyanoacetate 
• 459-44-9 4-methylbenzenediazonium tetrafluoroborate 
• 106-49-0 p-toluidine 

Downstream Products

• 1329681-95-9 ethyl 1-p-tolyl-5-(4-(3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-1-yl)-1H-1,2,4-triazole-3-carboxylate 
• 1329682-07-6 ethyl 5-(4-pentyl-1H-1,2,3-triazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329682-08-7 ethyl 5-(4-(methoxymethyl)-1H-1,2,3-triazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329682-09-8 ethyl 5-(4-tert-butyl-1H-1,2,3-triazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329681-82-4 ethyl 5-(2,4-diphenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329682-10-1 ethyl 5-(2-tert-butyl-4-phenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329682-11-2 ethyl 5-(2-benzyl-4-phenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329681-89-1 ethyl 5-(2-(2-methoxyphenyl)-4-phenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329682-12-3 ethyl 5-(2-(2-methoxyphenyl)-4-(4-methoxyphenyl)-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329682-13-4 ethyl 5-(4-(4-methoxyphenyl)-2-phenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329681-83-5 ethyl 5-(2-tert-butyl-4-(4-methoxyphenyl)-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329681-84-6 ethyl 5-(4-(3-fluorophenyl)-2-phenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329681-86-8 ethyl 5-(2-phenyl-4-(3-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 
• 1329681-88-0 ethyl 5-(2-(6-chlorohexyl)-4-phenyl-1H-imidazol-1-yl)-1-p-tolyl-1H-1,2,4-triazole-3-carboxylate 

Relevant articles and documents

Cycloaddition of Isocyanides with Aryl Diazonium Salts: Catalyst-Dependent Regioselective Synthesis of 1,3- and 1,5-Disubstituted 1,2,4-Triazoles

An unprecedented catalyst-dependent regioselective [3 + 2] cycloaddition of isocyanides with aryl diazonium salts is reported. 1,3-Disubstituted 1,2,4-triazoles were selectively obtained in high yield under Ag(I) catalysis, whereas 1,5-disubstituted 1,2,4-triazoles were formed by Cu(II) catalysis. These catalytic methodologies provide a controlled, modular, and facile access to 1,2,4-triazole scaffolds with high efficiency, broad substrate scope, and excellent functional group compatibility.