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1245645-62-8

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1245645-62-8 Usage

Description

L-beta-hoMoserine-HCl, also known as homoserine, is a non-proteinogenic amino acid that plays a significant role in the biosynthesis of methionine and threonine in plants and bacteria. It is a key intermediate in the production of various chemicals, including antibiotics, antiviral drugs, and herbicides, and is a vital component in the synthesis of vitamin B6. L-beta-hoMoserine-HCl is also used in the development of novel therapeutic agents and biochemical research.

Uses

Used in Pharmaceutical Industry:
L-beta-hoMoserine-HCl is used as a key intermediate for the production of various pharmaceuticals, such as antibiotics, antiviral drugs, and other therapeutic agents, due to its involvement in the biosynthesis of essential amino acids and its potential in the development of novel drugs.
Used in Chemical Industry:
L-beta-hoMoserine-HCl is used as a crucial component in the synthesis of various chemicals, including herbicides, due to its role as an intermediate in the production process.
Used in Vitamin Production:
L-beta-hoMoserine-HCl is used as a vital component in the synthesis of vitamin B6, which is essential for various metabolic processes in the human body.
Used in Biochemical Research:
L-beta-hoMoserine-HCl is used as a valuable compound in biochemical research, particularly in the study of amino acid metabolism, enzyme function, and the development of new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 1245645-62-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,6,4 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1245645-62:
(9*1)+(8*2)+(7*4)+(6*5)+(5*6)+(4*4)+(3*5)+(2*6)+(1*2)=158
158 % 10 = 8
So 1245645-62-8 is a valid CAS Registry Number.

1245645-62-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R)-3-amino-4-hydroxybutanoic acid,hydrochloride

1.2 Other means of identification

Product number -
Other names UNII-3VYM1G0Y0X

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1245645-62-8 SDS

1245645-62-8Relevant articles and documents

Design and preparation of serine-threonine protein phosphatase inhibitors based upon the nodularin and microcystin toxin structures: Part 2. Synthesis of a functionalised nodularin macrocycle and a stripped-down microcystin macrocycle

Maude, Antony B.,Mehrotra, Amit P.,Gani, David

, p. 2513 - 2526 (1997)

Nodularins and microcystins are complex natural isopeptidic hepatotoxins that serve as subnanomolar inhibitors of the eukaryotic serine-threonine protein phosphatases, PP1 and PP2A. In Part 1 (A. P. Mehrotra, K. L. Webster and D. Gani, J. Chem. Soc., Perkin Trans. 1, 1997, preceding paper) each of the key structural or potentially reactive motifs within each macrocycle type was assessed as a contributor towards phosphatase inhibitory efficacy and a stripped-down nodularin-type macrocycle was identified as a suitable precursor to potentially active synthetic inhibitors. Subsequently, synthetic routes to the 19-membered nodularin macrocyclic system were developed, using solution-phase chemistry, which demonstrated that only certain cyclisation protocols were viable. Here we describe an extension of this chemistry to provide a 19-membered nodularin macrocycle, cyclo-[(3R)-3-hydroxymethyl-β-Ala-(R)-Glu-α-OMe-γ-Sar-(R)-Asp- α-OMe-β-(S)-Phe-], appropriately functionalised with a hydroxymethyl group for the incorporation of lipophilic side-chains. We also demonstrate that the 25-membered microcystin macrocycle, cyclo-[β-Ala-(R)-Glu-α-OMe-γ-Sar-(R)-Ala-(S)-Leu-(R)-Asp- α-OMe-β-(S)-Phe-], can be prepared in good yield using similar protocols in which macrocyclisation is effected through the reaction of the amino group of the (2S)-phenylalanine residue with the β-pentafluorophenyl ester of the (2R)-aspartic acid residue.

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