1245648-27-4 Usage
General Description
The chemical 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylic acid is a carboxylic acid derivative containing a triazole ring substituted with a trifluoromethylphenyl group. It is commonly used as a building block for the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and potential biological activity. 1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylic acid has been studied for its potential as an anti-inflammatory, anticancer, and antifungal agent. Its unique structure and functional groups make it an important intermediate in the field of medicinal chemistry. Additionally, its trifluoromethyl substituent makes it a valuable tool for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1245648-27-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,6,4 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1245648-27:
(9*1)+(8*2)+(7*4)+(6*5)+(5*6)+(4*4)+(3*8)+(2*2)+(1*7)=164
164 % 10 = 4
So 1245648-27-4 is a valid CAS Registry Number.
1245648-27-4Relevant articles and documents
Design, synthesis and biological evaluation of glycolamide, glycinamide, and β-amino carbonyl 1,2,4-triazole derivatives as DPP-4 inhibitors
Fuh, Mao-Tsu,Tseng, Ching-Chun,Li, Sin-Min,Tsai, Shuo-En,Chuang, Tsung-Jui,Lu, Chih-Hao,Yang, Ya-Chen,Tsai, Henry J.,Wong, Fung Fuh
supporting information, (2021/06/21)
Through modification of the skeleton of Sitagliptin and Vildagliptin, we successfully synthesized and built-up four series of 1,2,4-triazole derivatives, containing N,O-disubstituted glycolamide, N,N′-disubstituted glycinamide, β-amino ester, and β-amino