124570-55-4

Basic information

• Product Name: 5-OXO-4,5-DIHYDROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBONITRILE
• Synonyms: 5-OXO-4,5-DIHYDROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBONITRILE
• CAS NO: 124570-55-4
• Molecular Formula: C11H6N4O
• Molecular Weight: 210.19
• Mol File: 124570-55-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 331.3±30.0 °C(Predicted)
• Appearance: /
• Density: 1.51±0.1 g/cm3(Predicted)
• PKA: 11.61±0.20(Predicted)
• CAS DataBase Reference: 5-OXO-4,5-DIHYDROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-OXO-4,5-DIHYDROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBONITRILE(124570-55-4)
• EPA Substance Registry System: 5-OXO-4,5-DIHYDROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBONITRILE(124570-55-4)

Safety Data

• Hazardous Substances Data: 124570-55-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 713, 1989 DOI: 10.1002/jhet.5570260335

Upstream product

• 610-94-6 2-bromobenzoic acid methyl ester 
• 16617-46-2 3-amino-4-cyano-2H-pyrazole 
• 393-52-2 2-Fluorobenzoyl chloride 
• 33906-30-8 2-hydrazinobenzoic acid hydrochloride 
• 123-06-8 Ethoxymethylenemalononitrile 

Downstream Products

• 124570-58-7 3-(1H-Tetrazol-5-yl)pyrazolo<1,5-a>quinazolin-5(4H)-one 
• 124570-60-1 5-(1-Piperidinyl)pyrazolo<1,5-a>quinazoline-3-carbonitrile 

Relevant articles and documents

Water-mediated selective synthesis of pyrazolo[1,5-a ]quinazolin-5(4 H)-ones and [1,2,4]triazolo[1,5-a ]quinazolin-5(4 H)-one via copper-catalyzed cascade reactions

A convenient and sustainable synthesis of pyrazolo[1,5-a]quinazolin-5(4H)-ones and [1,2,4]triazolo[1,5-a]quinazolin-5(4H)-one through copper-catalyzed cascade reactions of 2-bromobenzoates with 1H-pyrazol-5-amines or 1H-1,2,4-triazol-5-amine under ligand-

An unexpected aminolysis in the synthesis of 5-substituted 3-(1H-tetrazol-5-yl)pyrazolo[1,5-a]quinazolines

A synthetic route to 5-substituted 3-(1H-tetrazol-5-yl)pyrazolo[1,5-a]quinazolines is described. An unexpected displacement of a 4-morpholinyl group from the 5-position of this system occurred during tetrazole formation by the ammonia produced by in situ generation of hydrazoic acid from ammonium chloride and sodium azide.