1245720-68-6Relevant academic research and scientific papers
Alkynes to (E)-enolates using tandem catalysis: Stereoselective anti-aldol and syn-[3,3]-rearrangement reactions
Grimster, Neil P.,Wilton, Donna A.A.,Chan, Louis K.M.,Godfrey, Christopher R.A.,Green, Clive,Owen, Dafydd R.,Gaunt, Matthew J.
supporting information; experimental part, p. 6429 - 6436 (2010/10/19)
A new tandem catalysis strategy that transforms alkyne derivatives to (E)-enol-equivalents followed by stereoselective anti-selective aldol coupling or syn-selective [3,3]-rearrangement transformations is reported. The mechanism is thought to proceed through an interchanging series of Lewis acid and Bronsted acid catalyzed reactions via the intermediacy of a ketiminum ion species.
