1245746-96-6

Basic information

• Product Name: (4R,5S)-4-(methoxycarbonyl)-5-(2-naphthyl)-N-tosyl-2-imidazoline
• CAS NO: 1245746-96-6
• Molecular Weight: 408.478
• Mol File: 1245746-96-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S)-4-(methoxycarbonyl)-5-(2-naphthyl)-N-tosyl-2-imidazoline(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-4-(methoxycarbonyl)-5-(2-naphthyl)-N-tosyl-2-imidazoline(1245746-96-6)
• EPA Substance Registry System: (4R,5S)-4-(methoxycarbonyl)-5-(2-naphthyl)-N-tosyl-2-imidazoline(1245746-96-6)

Safety Data

• Hazardous Substances Data: 1245746-96-6(Hazardous Substances Data)

Upstream product

• 17692-84-1 N-(2-naphthylidene)-4-methylbenzenesulfonamide 
• 39687-95-1 isocyanoacetic acid methyl ester 

Relevant articles and documents

Organocatalytic asymmetric Mannich-type reaction of N-sulfonylimines with isocyanoacetate leading to optically active 2-imidazoline-4-carboxylates

The first asymmetric Mannich-type reaction of methyl isocyanoacetate with N-sulfonylimines catalyzed by cinchona alkaloid derivatives yielded 2-imidazolines with high diastereoselectivities and good enantioselectivities (up to >99:1 dr and 70% ee). This reaction provided a convenient route to access various substituted 2-imidazoline-4-carboxylates and related α,β-diamino acids in high enantiomeric purities.