1245773-38-9

Basic information

• Product Name: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(4-nitrobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
• Synonyms: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(4-nitrobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
• CAS NO: 1245773-38-9
• Molecular Weight: 580.514
• Mol File: 1245773-38-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(4-nitrobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(4-nitrobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(1245773-38-9)
• EPA Substance Registry System: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(4-nitrobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(1245773-38-9)

Safety Data

• Hazardous Substances Data: 1245773-38-9(Hazardous Substances Data)

Upstream product

• 17271-88-4 p-nitrobenzyl azide 
• 91077-93-9 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-ethynyl-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 

Downstream Products

• 1245773-50-5 (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(1-(4-nitrobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol 

Relevant articles and documents

Expeditious synthesis and biological evaluation of new C-6 1,2,3-triazole adenosine derivatives A1 receptor antagonists or agonists

The synthesis of new C-6 1,2,3-triazole adenosine derivatives via microwave assisted 1,3-dipolar cycloaddition as key step is described. The binding on membranes of cells that over express A1 adenosine receptors (A 1AR) was also evaluated. Among them, four compounds increased cAMP production, in a dose-dependent manner acting as antagonists of the A 1AR, while two compounds act as agonists.