1245773-47-0

Basic information

• Product Name: (2R,3R,4S,5R)-2-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
• Synonyms: (2R,3R,4S,5R)-2-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
• CAS NO: 1245773-47-0
• Molecular Weight: 488.3
• Mol File: 1245773-47-0.mol

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S,5R)-2-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S,5R)-2-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol(1245773-47-0)
• EPA Substance Registry System: (2R,3R,4S,5R)-2-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol(1245773-47-0)

Safety Data

• Hazardous Substances Data: 1245773-47-0(Hazardous Substances Data)

Upstream product

• 1245773-34-5 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 

Relevant articles and documents

Expeditious synthesis and biological evaluation of new C-6 1,2,3-triazole adenosine derivatives A1 receptor antagonists or agonists

The synthesis of new C-6 1,2,3-triazole adenosine derivatives via microwave assisted 1,3-dipolar cycloaddition as key step is described. The binding on membranes of cells that over express A1 adenosine receptors (A 1AR) was also evaluated. Among them, four compounds increased cAMP production, in a dose-dependent manner acting as antagonists of the A 1AR, while two compounds act as agonists.