1245909-24-3Relevant academic research and scientific papers
A facile synthesis of N/C-terminal selenourea tethered glycosylated amino acids
Sureshbabu, Vommina V.,Vasantha,Madhu
, p. 895 - 900 (2013/08/15)
A simple route for the synthesis of a new class of neoglycosylated amino acids possessing a selenourea moiety is described. The coupling of a-isoselenocyanato esters or Cbz/Boc-amino alkyl isoselenocyanates with peracetyl/benzoylated glucosylamine at ambient temperature led to insert selenourea as a linker. All the compounds prepared have been isolated as analytically pure ones, and characterized by 1H. 13C and 77Se NMR, and mass spectroscopy.
Isoselenocyanates derived from Boc/Z-amino acids: Synthesis, isolation, characterization, and application to the efficient synthesis of unsymmetrical selenoureas and selenoureidopeptidomimetics
Chennakrishnareddy, Gundala,Nagendra, Govindappa,Hemantha, Hosahalli P.,Das, Ushati,Guru Row, Tayur N.,Sureshbabu, Vommina V.
supporting information; experimental part, p. 6718 - 6724 (2010/09/30)
Isoselenocyanates derived from Boc/Z-amino acids are prepared by the reaction of the corresponding isonitriles with selenium powder in presence of triethylamine at reflux. The utility of these new classes of isoselenocyanates in the preparation of selenoureidodipeptidomimetics possessing both amino as well as carboxy termini has been accomplished. The 1H NMR analysis confirmed that the protocol involving the conversion of isonitriles to isoselenocyanates and their use as coupling agents in assembling selenoureido derivatives is free from racemization.
