1245924-69-9Relevant academic research and scientific papers
Synthesis of unfunctionalized carbonated fragments containing two vicinal chiral centers: Stereocontrolled benzylation of vinylsulfones mediated by a remote sulfinyl group
Ruano, Jose Luis Garcia,Schoepping, Christine,Alvarado, Cuauhtemoc,Aleman, Jose
supporting information; experimental part, p. 8968 - 8971 (2010/10/02)
One-pot benzylation of (E)-vinylsulfones with optically pure 2-p-tolylsulfinylbenzyl carbanions and desulfinylation with tBuLi, followed by desulfonylation of the resulting 1-sulfonylpropanes, provided acyclic hydrocarbons containing two connected chiral centers in very smooth conditions and almost complete control of the stereoselectivity (see scheme).
