124595-23-9Relevant academic research and scientific papers
Synthesis, biological evaluation and structure-activity relationship studies of hederacolchiside E and its derivatives as potential anti-Alzheimer agents
Li, Hui-ning,Liu, Yang,Zhang, Zuo-peng,Wang, Zhi-peng,Hao, Jing-zheng,Li, Feng-ran,Fan, Zhan-fang,Zou, Li-bo,Cheng, Mao-sheng
, p. 376 - 389 (2018)
Inspired by the previously reported neuroprotective activity of hederacolchiside E (1), we synthesized hederacolchiside E for the first time along with eleven of its derivatives. The neuroprotective effects of these compounds were further evaluated agains
Access to Galectin-3 Inhibitors from Chemoenzymatic Synthons
Dussouy, Christophe,Téletchéa, Stéphane,Lambert, Annie,Charlier, Cathy,Botez, Iuliana,De Ceuninck, Frédéric,Grandjean, Cyrille
, p. 16099 - 16114 (2020/12/01)
Chemoenzymatic strategies are useful for providing both regio- and stereoselective access to bioactive oligosaccharides. We show herein that a glycosynthase mutant of a Thermus thermophilus α-glycosidase can react with unnatural glycosides such as 6-azido
FACILE SYNTHESIS OF SILYLATED THIOGLYCOSIDES
Nambiar, Sudhir,Daeuble, John F.,Doyle, Ronald J.,Taylor, K. Grant
, p. 2179 - 2182 (2007/10/02)
The one pot conversion of 1,2,4,6-tetra-O-acetyl-β-D-glucopyranose, 1, into phenyl 2,4,6-tri O-acetyl-3-O-trialkylsilyl-1-thio-β-D-glucopyranosides, 3, is described.The method is applicable to use with galactopyranosyl-, 2-deoxyglucopyranosyl-, and ribofuranosyl-starting materials.
