1246010-98-9

Basic information

• Product Name: C₁₃H₁₂IN₃O₂S
• Synonyms: C₁₃H₁₂IN₃O₂S
• CAS NO: 1246010-98-9
• Molecular Weight: 401.228
• Mol File: 1246010-98-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₂IN₃O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₂IN₃O₂S(1246010-98-9)
• EPA Substance Registry System: C₁₃H₁₂IN₃O₂S(1246010-98-9)

Safety Data

• Hazardous Substances Data: 1246010-98-9(Hazardous Substances Data)

Upstream product

• 315672-60-7 2-methyl-furan-3-carboxylic acid hydrazide 
• 2059-76-9 4-iodophenyl isothiocyanate 

Downstream Products

• 1246011-01-7 C₁₃H₁₀IN₃OS 

Relevant articles and documents

1,4-disubstituted thiosemicarbazide derivatives are potent inhibitors of toxoplasma gondii proliferation

A series of 4- Arylthiosemicarbazides substituted at the N1 position with a 5-membered heteroaryl ring was synthesized and evaluated in vitro for T. gondii inhibition proliferation and host cell cytotoxicity. At non- Toxic concentrations for the host cells all studied compounds displayed excellent anti-parasitic effects when compared to sulfadiazine, indicating a high selectivity of their anti-T. gondii activity. The differences in bioactivity investigated by DFT calculations suggest that the inhibitory activity of 4- Arylthiosemicarbazides towards T. gondii proliferation is connected with the electronic structure of the molecule. Further, these compounds were tested as potential antibacterial agents. No growth-inhibiting effect on any of the test microorganisms was observed for all the compounds, even at high concentrations.