1246014-07-2Relevant academic research and scientific papers
Discovery of novel sphingosine kinase-1 inhibitors. Part 2
Xiang, Yibin,Hirth, Bradford,Kane Jr., John L.,Liao, Junkai,Noson, Kevin D.,Yee, Christopher,Asmussen, Gary,Fitzgerald, Maria,Klaus, Christine,Booker, Michael
scheme or table, p. 4550 - 4554 (2010/09/14)
Building on our initial work, we have identified additional novel inhibitors of sphingosine kinase-1 (SK1). These new analogs address the shortcomings found in our previously reported compounds. Inhibitors 51 and 54 demonstrated oral bioavailability in a
