124603-86-7

Upstream product

• 1035817-16-3 2-(acetyloxy)-1-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>ethanone 
• 19493-09-5 Methylenetriphenylphosphorane 
• 97826-90-9 cis-2-(acetyloxy)-1-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>ethanone 
• 105-13-5 4-Methoxybenzyl alcohol 
• 38982-28-4 1-acetoxybut-3-en-2-one 

Downstream Products

• 111675-14-0 C₃₄H₃₅O₆P 
• 111675-14-0 C₃₄H₃₅O₆P 
• 124649-59-8 (2R,2'S,3'aR,6'S,7'aR,4''S,5''R)-decahydro-4''-<<3-(diphenylphosphinyl)benzoyl>oxy>-5''-methyldispiropyran>-6'-carboxaldehyde 
• 111767-81-8 C₃₄H₃₅O₆P 
• 111675-15-1 C₃₄H₃₅O₆P 
• 97826-93-2 (3R,4S)-5<(tert-butyldimethylsilyl)oxy>3-hydroxy-1-<2(R)-<2(R)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranyl>-4-methyl-1-pentanone 
• 97905-63-0 (3S,4S)-5<(tert-butyldimethylsilyl)oxy>3-hydroxy-1-<2(R)-<2(R)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranyl>-4-methyl-1-pentanone 
• 124649-54-3 (3R,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-1-[(R)-2-((1S,2R)-2-hydroxy-cyclohex-3-enyl)-oxiranyl]-4-methyl-pentan-1-one 
• 124603-90-3 (3S,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-1-[(R)-2-((1S,2R)-2-hydroxy-cyclohex-3-enyl)-oxiranyl]-4-methyl-pentan-1-one 
• 124603-99-2 C₃₄H₃₅O₆P 
• 111675-18-4 C₃₃H₃₃O₆P 
• 111692-60-5 (2R,2'S,3'aR,7'aR,4''S,5''R)-4''-<<3-(diphenylphosphino)benzoyl>oxy>-5''-methyl-3'a,6',7',7'a,3'',4'',5'',6''-octahydrodispiropyran> 
• 111692-59-2 (2R,2'S,3'aR,7'aR,4''S,5''R)-4''-<<4-(diphenylphosphino)benzoyl>oxy>-5''-methyl-3'a,6',7',7'a,3'',4'',5'',6''-octahydrodispiro-pyran> 
• 124603-88-9 3-tert-Butoxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-cyclohex-3-enyl]-propane-1,2-diol 

Relevant academic research and scientific papers

Total Synthesis of (+)-Phyllanthocin. Introduction of Intramolecular Hydroformylation for Complex Molecule Functionalization

A 17-step total synthesis of (+)-phyllanthocin (1a) is described.Application of Sharpless'asymetric epoxidation reaction provided access to the diastereo- and enantiomerically pure epoxy ketone 9, a partner in crossed aldol construction.A notably rapid and high-yielding spiroketal equilibration leading to the tetracyclic intermediate 2 was effected with HF in acetonitrile.A Rh(I)-catalyzed hydroformylation was used to introduce the C3 functionality.Studies of intramolecular delivery of the rhodium nucleus to the concave face of the C3-C4 olefin led to a substantial improvement in yield and regioselectivity over the intermolecular version.