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4-Iodo-1,5-naphthyridin-3-ol is a chemical compound belonging to the class of naphthyridines, which are fused nitrogen-containing heterocycles. It is characterized by the presence of an iodine atom at the 4-position and a hydroxyl group at the 3-position. 4-Iodo-1,5-naphthyridin-3-ol is known for its potential applications in the pharmaceutical and chemical industries due to its unique structural features and reactivity.

1246088-57-2

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1246088-57-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Iodo-1,5-naphthyridin-3-ol is used as a key intermediate in the synthesis of monoand polyazanaphthalene derivatives. These derivatives have been identified as potent inhibitors of MNK1 kinase, a protein involved in the regulation of eukaryotic initiation factor 4E (eIF4E). Inhibition of MNK1 kinase has been shown to have therapeutic potential in the treatment of various diseases, including cancer and inflammatory disorders.
The compound's ability to act as a precursor for the development of MNK1 kinase inhibitors makes it a valuable asset in the pharmaceutical industry, where it can contribute to the discovery and development of novel therapeutic agents for a range of medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1246088-57-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,0,8 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1246088-57:
(9*1)+(8*2)+(7*4)+(6*6)+(5*0)+(4*8)+(3*8)+(2*5)+(1*7)=162
162 % 10 = 2
So 1246088-57-2 is a valid CAS Registry Number.

1246088-57-2 Well-known Company Product Price

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  • Aldrich

  • (ADE000865)  4-Iodo-1,5-naphthyridin-3-ol  AldrichCPR

  • 1246088-57-2

  • ADE000865-1G

  • 9,342.45CNY

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1246088-57-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Iodo-1,5-naphthyridin-3-ol

1.2 Other means of identification

Product number -
Other names 4-iodo-5H-1,5-naphthyridin-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1246088-57-2 SDS

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