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1246213-41-1

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1246213-41-1 Usage

Description

3-Quinolinecarboxamide, N-[5-(1,1-dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxo-, also known as Ivacaftor Carboxylic Acid Lactone, is a chemical compound derived from quinoline carboxamides. It is structurally related to Ivacaftor, a medication used for the treatment of cystic fibrosis. 3-QuinolinecarboxaMide, N-[5-(1,1-diMethylethyl)-2,3-dihydro-3,3-diMethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxoexhibits potential therapeutic properties and is being investigated for its applications in various fields.

Uses

Used in Pharmaceutical Industry:
3-Quinolinecarboxamide, N-[5-(1,1-dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxois used as an active pharmaceutical ingredient for the development of medications targeting specific diseases. Its structural similarity to Ivacaftor suggests that it may have potential applications in the treatment of cystic fibrosis or other related conditions.
Used in Research and Development:
In the field of research and development, 3-Quinolinecarboxamide, N-[5-(1,1-dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxoserves as a valuable compound for studying its chemical properties, potential interactions with biological systems, and possible therapeutic effects. This research can lead to the discovery of new drugs and treatment strategies for various diseases.
Used in Drug Synthesis:
3-Quinolinecarboxamide, N-[5-(1,1-dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxois used as a key intermediate in the synthesis of other pharmaceutical compounds. Its unique structure and properties make it a valuable building block for the development of new drugs with improved efficacy, safety, and selectivity.

Check Digit Verification of cas no

The CAS Registry Mumber 1246213-41-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,2,1 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1246213-41:
(9*1)+(8*2)+(7*4)+(6*6)+(5*2)+(4*1)+(3*3)+(2*4)+(1*1)=121
121 % 10 = 1
So 1246213-41-1 is a valid CAS Registry Number.

1246213-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(5-tert-butyl-3,3-dimethyl-2-oxo-1-benzofuran-6-yl)-4-oxo-1H-quinoline-3-carboxamide

1.2 Other means of identification

Product number -
Other names N-(5-(tert-Butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1246213-41-1 SDS

1246213-41-1Relevant articles and documents

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

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Page/Page column 75; 78-79, (2010/10/03)

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 3; in the presence of a coupling agent.

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