1246224-45-2Relevant academic research and scientific papers
Synthesis and Characterisation of Chiral Triazole-Based Halogen-Bond Donors: Halogen Bonds in the Solid State and in Solution
Kaasik, Mikk,Kaabel, Sandra,Kriis, Kadri,J?rving, Ivar,Aav, Riina,Rissanen, Kari,Kanger, T?nis
supporting information, p. 7337 - 7344 (2017/05/31)
A general platform for the synthesis of various chiral halogen-bond (XB) donors based on the triazole core and the characterisation of factors that influence the strength of the halogen bond in the solid state and in solution are reported. The characterisation of XB donors in the solid state by X-ray crystallography and in solution by 1H NMR titration can be used to aid the design of new XB donors. We describe the first example of a XB between iodotriazoles and thioureas in solution. In addition, the enantiodiscrimination of acceptors in solution through halogen-bond participation is described.
Highly efficient two-step synthesis of (Z)-2-halo-1-iodoalkenes from terminal alkynes
Chen, Zhengwang,Jiang, Huanfeng,Li, Yibiao,Qi, Chaorong
supporting information; experimental part, p. 8049 - 8051 (2011/01/03)
The easily accessible haloalkynes can be converted to (Z)-2-halo-1- iodoalkenes in high yields with excellent regio- and stereoselectivity. The method shows good functional group compatibility. The resulting products could find broad applications.
