1246226-60-7

Basic information

• Product Name: methyl 3-amino-5-(4-formylphenyl)-4-methylthiophene-2-carboxylate
• Synonyms: methyl 3-amino-5-(4-formylphenyl)-4-methylthiophene-2-carboxylate
• CAS NO: 1246226-60-7
• Molecular Weight: 275.328
• Mol File: 1246226-60-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-amino-5-(4-formylphenyl)-4-methylthiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-amino-5-(4-formylphenyl)-4-methylthiophene-2-carboxylate(1246226-60-7)
• EPA Substance Registry System: methyl 3-amino-5-(4-formylphenyl)-4-methylthiophene-2-carboxylate(1246226-60-7)

Safety Data

• Hazardous Substances Data: 1246226-60-7(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 85006-31-1 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester 

Relevant articles and documents

Palladium-catalyzed direct arylation using free NH2 substituted thiophene derivatives with inhibition of amination type reaction

The palladium-catalyzed direct arylation at C2 or C5 of free NH2 substituted thiophene derivatives was found to proceed in moderate to high yields using a variety of aryl halides. The choice of potassium acetate as the base was found to be crucial to inhibit the amination reaction and to promote the direct arylation.