1246266-85-2Relevant academic research and scientific papers
Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
Vintonyak, Viktor V.,Warburg, Karin,Over, Bj?rn,Hübel, Katja,Rauh, Daniel,Waldmann, Herbert
, p. 6713 - 6729 (2011/10/01)
Tuberculosis continues to be a major cause of morbidity and mortality throughout the world. Protein tyrosine phosphatases from Mycobacterium tuberculosis are attractive targets for developing novel strategies in battling tuberculosis due to their role in
Identification of Thiazolidinones Spiro-Fused to IndoIin-2-ones as Potent and Selective Inhibitors of the Mycobacterium tuberculosis Protein Tyrosine Phosphatase B
Vintonyak, Viktor V.,Warburg, Karin,Kruse, Holger,Grimme, Stefan,Huebet, Katja,Rauh, Daniel,Waldmann, Herbert
supporting information; experimental part, p. 5902 - 5905 (2010/10/19)
(Figure Presented) The best of 40000: Detailed structureactivity- relationship studies revealed key structural elements of indolin-2-on-3- spirothiazolidinones (see example) and their appropriate configuration for strong inhibitory activity against the pa
